In the IRAD series, 67% of patients presented with type A AAD, with the remaining 33% type B. This review will cover most of these points, highlighting the critical findings of the IRAD that have been published over these past 2 decades. IRAD investigators have published >80 articles derived from the large database of patients with AAD of >7300 cases, thus far, to raise awareness of this difficult-to-diagnose entity and provide insights regarding optimal diagnosis and management. Since the first publication in 2000 with the participation of 12 large referral centers in 6 countries, the IRAD has expanded to 51 active sites in 12 countries in North America, Europe, Asia, and Australia. These forms were analyzed by the IRAD Coordinating Center at the University of Michigan 1 for face validity and then entered into a secure online database. Data on demographics, presenting history, physical examination, imaging studies, management, and outcomes were collected by each referral center ( Figure I in the online-only Data Supplement) and entered on case report forms covering 350 variables using standard definitions and methods. The International Registry of Acute Aortic Dissection (IRAD) was established in 1996 for the purpose of enrolling a large number of patients at a number of aortic centers to assess the presentation, management, and outcomes of AAD.
Journal of the American Heart Association (JAHA).
Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
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